Question: I'm looking for a solution that enables autonomous flight without GPS navigation or human pilots.

If you're looking for a system that can fly autonomously with no GPS or human pilots, Shield AI has a compelling option. Its Hivemind AI pilot system can fly on its own with no GPS or human pilots, and it's good for a lot of things, including military missions, civilian logistics and cargo transport. It's already proven itself for tasks like clearing buildings and penetrating air defenses, and it can be adapted to different aircraft bodies like drones and jets.

Another interesting project is Skydio, which offers advanced aerial robotics for Defense, Public Safety and Energy & Utilities customers. Its self-piloting drones use AI and high-resolution cameras to fly on their own and gather data in complex environments. They can be piloted remotely and work in a variety of environments, making important work safer and more productive.

For medical and commercial uses, Matternet has an autonomous drone network for package delivery. The system includes FAA Type Certification, M2 drones that can carry payloads for up to 20km, and a software platform for routing flights and tracking assets. Matternet's system is designed to deliver medical supplies and e-commerce packages quickly with zero emissions, a potentially more economical and environmentally friendly alternative to traditional delivery.