Audioshake is an AI-powered audio separation tool that's good at extracting stems from an audio file. It's got a lot of other tools, too, like mixing and mastering, audio analysis and interactive tools, but the audio element recognition is useful for making instrumentals and for improving transcription quality.
Cryo Mix is another good tool with an AI Audio Separator that'll pull out stems like vocals, drums and instruments from an audio file. It's got mixing and mastering tools, too, so it's a good all-purpose tool for improving audio. Its interface is simple enough that you don't have to be an audio expert to get good results.
If you need fast and reliable stem separation, LALAL.AI offers a service that splits audio files into high-quality vocal and instrumental tracks. You can upload multiple files, and it works with lots of audio file formats. Results are fast, often in seconds. It's good for musicians, streamers and anyone else who needs to separate audio tracks accurately and quickly.